Prevention of Maternal and Congenital Cytomegalovirus Infection
نویسندگان
چکیده
منابع مشابه
Maternal immunity and prevention of congenital cytomegalovirus infection.
CONTEXT Vaccine development to prevent congenital cytomegalovirus (CMV) infection has been impeded by the uncertainty over whether maternal immunity protects the fetus. OBJECTIVE To determine whether the presence of maternal antibodies to CMV significantly reduces the risk of congenital CMV infection in future pregnancies. DESIGN, SETTING, AND PARTICIPANTS Cohort study of 3461 multiparous w...
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Human cytomegalovirus (CMV) is one of the eight viruses belonging to the Herpesviridae family to infect humans. CMV belongs to the Betaherpesvirinae subfamily of viruses characterized by a restricted host spectrum, in vitro replication in fibroblasts of the natural host species in vivo, a slow replication cycle, the induction of intranuclear and intracytoplasmic inclusions and the ability to in...
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In a prospective study of cytomegalovirus (CMV) infection in pregnancy 69 congenitally infected infants were identified. The age, race, marital status, social class, and parity of the mothers of congenital CMV infants were compared with those of the screened population of women with non-infected infants. These factors were all individually strongly associated with the prevalence of congenital C...
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Human cytomegalovirus (CMV) infection is the most common cause of perinatal viral infection in the developed world, resulting in approximately 40,000 congenitally infected infants in the United States each year. Congenital CMV infection can produce varying degrees of neurodevelopmental disabilities. The significant impact of congenital CMV has led the Institute of Medicine to rank development o...
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Congenital cytomegalovirus infection is a major cause of central nervous system and sensory impairments that affect cognition, motor function, hearing, language development, vestibular function, and vision. Although the importance of congenital cytomegalovirus infection is readily evident, the vast majority of maternal and fetal infections are not identified, even in developed countries. Multip...
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ژورنال
عنوان ژورنال: Clinical Obstetrics & Gynecology
سال: 2012
ISSN: 0009-9201
DOI: 10.1097/grf.0b013e3182510b7b